Article

<i>TelNet</i> - a database for human and yeast genes involved in telomere maintenance

2017-04-27

Abstract excerpt

The ends of linear chromosomes, the telomeres, comprise repetitive DNA sequences that are protected by the shelterin protein complex. Cancer cells need to extend these telomere repeats for their unlimited proliferation, either by reactivating the reverse transcriptase telomerase or by using the alternative lengthening of telomeres (ALT) pathway. The different telomere maintenance (TM) mechanisms appear to involve...

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Literature Corpus work: 0fd1d42c-dfe1-5ff2-8310-f64a51a00c77
DOI: 10.1101/130153

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