Article

Control of mitochondrial dynamics by dPGC1 limits Yorkie-induced oncogenic growth in <i>Drosophila</i>

2024-12-02

Abstract excerpt

Mitochondrial function and dynamics are essential for maintaining cellular homeostasis and overall health. Disruptions in these processes can contribute to various diseases, including cancer. The Hippo signaling pathway, a key regulator of tissue growth, plays a central role in cancer through its main effector, the Yes-associated protein (YAP), known as Yorkie (Yki) in Drosophila . In this model organism, Yki up...

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Literature Corpus work: 11eea755-4154-5475-aa05-1971218d430e
DOI: 10.1101/2024.12.02.626378

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