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<i>Drp1-JNK</i> knockdown mitigates Scribble loss induced cell proliferation, metastasis and lethality phenotypes in <i>Drosophila</i>

2024-04-13

Abstract excerpt

Mitochondrial dynamics are emerging as master regulators for targeting several types of cancers, including breast cancer, cervical cancer, and hepatocellular carcinoma, for therapeutic intervention. Mitochondrial morphology, size, position and activity within cells is regulated by dynamic fission and fusion events. Dynamin-related protein 1 ( Drp1 ) promotes mitochondrial fission and maintains mitochondrial homeo...

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Literature Corpus work
ab92de3a-0c55-553a-831b-accee5376491
DOI
10.1101/2024.04.10.588977
Open publication

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