Article

Somatic mutations in chronic lung disease are associated with reduced lung function

2023-03-05

Abstract excerpt

Among human organs, the lung harbors one of the highest rates of somatic mutations. However, the relationship of these mutations to lung disease and function is not known. We analyzed the somatic mutational pattern from 1,251 samples of normal and diseased non-cancerous lung tissue from the Lung Tissue Research Consortium using RNA-seq. In two of the most common diseases represented in our dataset, chronic obstruc...

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Literature Corpus work: 11c623d3-ef17-5963-a761-040b3133b876
DOI: 10.1101/2023.03.03.23286771

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