Article

Multi-omics reveals changes in astrocyte fatty acid metabolism during early stages of Alzheimer's disease

2024-09-26

Abstract excerpt

<title>Abstract</title> <p>Background Astrocytes undergo extensive changes during Alzheimer's disease (AD), including reactive transformations induced by Aβ deposition and adjustments in lipid metabolism, ion balance, neuronal support, and inflammatory responses. Although dysfunctional astrocytes are known to contribute to AD progression, a detailed characterization of the dynamic alterations in astrocytes at th...

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Literature Corpus work: 1135c75b-40a8-511b-8f79-93b4655fe54e
DOI: 10.21203/rs.3.rs-4976800/v1

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