Article

Mapping the evolutionary landscape of Zika virus infection in immunocompromised mice

2019-11-13

Abstract excerpt

The fundamental basis of how arboviruses evolve in nature and what regulates the adaptive process remain unclear. To address this problem, we established a Zika virus (ZIKV) vector-borne transmission system in immunocompromised mice that mimics evolutionary characteristics of ZIKV infection in humans. Using this system, we defined factors that influence the evolutionary landscape of ZIKV infection and show that tr...

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Identifiers and source

Literature Corpus work: 10db37df-99d6-50a0-8050-dd22facf7d12
DOI: 10.1101/839803

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