Article

ATGL-LC3B-Lipid Complexes Mediate Lipophagy-Driven Radioprotection Against Metabolic Liver Injury in Adolescents

2025-08-08

Abstract excerpt

<title>Abstract</title> <p>Radiation-induced liver disease (RILD) poses a significant clinical challenge, particularly in adolescents with hepatocellular carcinoma, where mortality exceeds 70%. Radiation disrupts lipid-protein homeostasis, but its interaction with selective autophagic pathways such as lipophagy, a lipid droplet degradation process critical for metabolic balance, remains unexplored in adolescent m...

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Literature Corpus work: 10d31363-7e0f-5f3a-9572-27e56b90c94a
DOI: 10.21203/rs.3.rs-7033545/v1

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