Back to search

Article

The identification of genes related to METTL14 inhibition in radiation- induced hepatocyte death based on bioinformatics analysis

2026-03-24

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Radiation-Induced Liver Disease (RILD) is a major dose-limiting complication in radiotherapy for hepatocellular carcinoma, yet its molecular mechanisms remain incompletely understood compared to radiation injury in other organs. Programmed cell death (PCD) pathways like apoptosis, pyroptosis, and ferroptosis are crucial in RILD development. The m6A modificati...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8e026001-788c-5e75-a623-00810c3600d0
DOI
10.21203/rs.3.rs-8087326/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The identification of genes related to METTL14 inhibition in radiation- induced hepatocyte death based on bioinformatics analysisDOI 10.21203/rs.3.rs-8087326/v1
Radiation-induced liver disease: beyond DNA damageSemantic proximity
CLTRN, regulated by NRF1/RAN/DLD protein complex, enhances radiation sensitivity of hepatocellular carcinoma cells through ferroptosis pathwaySemantic proximity
Ferroptosis, autophagy, pyroptosis, and necroptosis in the occurrence and development of radiation-induced lung injurySemantic proximity
Long non-coding RNA NORAD serves as a promoter of oncogenesis and inhibits ferroptosis via miR-144-3p-mTOR-ferritinophagy axis in cancerSemantic proximity
Assessment of Radiation Induced Therapeutic Effect and Cytotoxicity in Cancer Patients Based on Transcriptomic ProfilingSemantic proximity
Analysis of lncRNA-miRNA-mRNA Expression Pattern in Heart Tissue After Total Body Irradiation in a Mouse ModelSemantic proximity
Targeting the TRIM14/USP14 axis enhances radiotherapy efficacy by inducing GPX4 degradation and disrupting ferroptotic defense in HCCSemantic proximity
Dual-stress-responsive-pathways prevent HCC initiation via p53 suppression of MTHFD1L-RNA m6A-elicited autonomous growth and immune evasionSemantic proximity
Investigating the Role of Chromatin Remodeler FOXA1 in Ferroptotic Cell DeathSemantic proximity
ATGL-LC3B-Lipid Complexes Mediate Lipophagy-Driven Radioprotection Against Metabolic Liver Injury in AdolescentsSemantic proximity
Glutamine Transporter SLC1A5 Regulates Ionizing Radiation‐Derived Oxidative Damage and FerroptosisSemantic proximity
TLR4-dependent immune response promotes radiation-induced liver disease by changing the liver tissue interstitial microenvironment during liver cancer radiotherapy.Semantic proximity
Select a neighboring publication to make it the new centre.