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Article

Microlipophagy-mediated lipid remodeling contributes to radioresistant phenotypes in small cell lung cancer.

Archives of biochemistry and biophysics - 1 Aug 2026

Dai Hui, Duan Siyu, Bao Xin, Lu Jiuqin, Ning Xia, Zhang Qin

Abstract excerpt

BACKGROUND: Small-cell lung cancer (SCLC) is a highly aggressive malignancy characterized by frequent recurrence, in which radiotherapy remains a cornerstone treatment. However, the development of radioresistance severely limits its efficacy. Emerging evidence suggests that autophagy, particularly microlipophagy, contributes to cellular stress adaptation and therapeutic resistance, but its role in SCLC...

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PMID: 42162650
DOI: 10.1016/j.abb.2026.110868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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