Article

Inhibition of p107 alleviates liver steatosis by reducing de novo fatty acid synthesis

2026-04-16

Abstract excerpt

Metabolic dysfunction–associated steatotic liver disease (MASLD) is characterized by excessive hepatic lipid accumulation driven by increased de novo lipogenesis (DNL) and impaired lipid oxidation. p107, a member of the retinoblastoma (Rb) family, extensively studied in the context of cell cycle regulation and adipocyte differentiation recently has been identified as a metabolic regulator controlling thermogenic a...

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Literature Corpus work: 0ee1a6e4-cedf-5944-be0a-cc7d0ff0b892
DOI: 10.64898/2026.04.14.718271

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