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Sphingolipid Regulation of Genome Stability: Stress Signaling, Chromatin Control, and Organelle Dysfunction

2026-06-05

Abstract excerpt

Sphingolipid metabolism has emerged as a regulatory interface between lipid homeostasis, organelle stress, and genome maintenance. Although sphingolipids are essential structural components of cellular membranes, specific metabolites also function as bioactive mediators that shape cellular responses to genotoxic stress. In this review, we examine how canonical and atypical sphingolipid pathways influence the DNA d...

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Literature Corpus work
0a9da3e3-07fe-57d4-8bc2-39b775e38655
DOI
10.20944/preprints202606.0422.v1
Open publication

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Sphingolipid Regulation of Genome Stability: Stress Signaling, Chromatin Control, and Organelle DysfunctionDOI 10.20944/preprints202606.0422.v1
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