Article

Two pathways of p27 <sup>Kip1</sup> degradation are required for murine lymphoma driven by Myc and EBV latent membrane protein 2A

2019-03-04

Abstract excerpt

Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A), expressed in EBV latency, contributes to Burkitt Lymphoma (BL) development in a murine model by acting as a constitutively active B cell receptor (BCR) mimic. Mice expressing both LMP2A and MYC transgenes (LMP2A/λ- MYC ) develop tumors significantly faster than mice only expressing MYC (λ- MYC ). Previously, we demonstrated the cell cycle inhibitor p...

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Literature Corpus work: 10a85fc2-2b61-5ffc-8704-28cd985649bf
DOI: 10.1101/564559

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