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Epstein-Barr virus in Burkitt’s lymphoma: A role for latent membrane protein 2A

1 Mar 2010

Abstract excerpt

Burkitt's lymphoma (BL) is characterized by translocation of the MYC gene to an immunoglobulin locus. Transgenic mouse models have been used to study the molecular changes that are necessary to bypass tumor suppression in the presence of translocated MYC. Inactivation of the p53 pathway is a major step to tumor formation in mouse models that is also seen in human disease. Human BL is often highly associated with...

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PMID: 20160479
DOI: 10.4161/cc.9.5.10840

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Epstein-Barr virus in Burkitt’s lymphoma: A role for latent membrane protein 2APMID 20160479Read ↗

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