Article

Brain-wide transcriptome-based metabolic alterations in Parkinson’s disease: human inter-region and human-experimental model correlations

2022-09-02

Abstract excerpt

Alterations in brain metabolism are closely associated with the molecular hallmarks of Parkinson’s disease (PD). A clear understanding of the main metabolic perturbations in PD is therefore important. Here, we retrospectively analysed the expression of metabolic genes from 34 PD-control post-mortem human brain transcriptome data from literature, spanning multiple brain regions, and found significant metabolic corr...

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Literature Corpus work: 1074c270-e18f-5c46-b17f-755c2524a468
DOI: 10.1101/2022.08.31.505965

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