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Article

Omics data integration suggests a potential idiopathic Parkinson’s disease signature

20 Nov 2023

Abstract excerpt

The vast majority of Parkinson's disease cases are idiopathic. Unclear etiology and multifactorial nature complicate the comprehension of disease pathogenesis. Identification of early transcriptomic and metabolic alterations consistent across different idiopathic Parkinson's disease (IPD) patients might reveal the potential basis of increased dopaminergic neuron vulnerability and primary disease mechanisms. In...

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PMID: 37985891
DOI: 10.1038/s42003-023-05548-w

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