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Metabolomics of blood reveals age-dependent pathways in Parkinson’s Disease

6 Jul 2022

Abstract excerpt

BACKGROUND: Parkinson's Disease (PD) is the second most frequent degenerative disorder, the risk of which increases with age. A preclinical PD diagnostic test does not exist. We identify PD blood metabolites and metabolic pathways significantly correlated with age to develop personalized age-dependent PD blood biomarkers. RESULTS: We found 33 metabolites producing a receiver operating characteristic (ROC) area...

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PMID: 35794650
DOI: 10.1186/s13578-022-00831-5

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