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Article

Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington’s disease

2020-08-07

Abstract excerpt

<h4>Background</h4> Converging lines of evidence from cell, yeast and animal models, and post-mortem human brain tissue studies, support the involvement of the kynurenine pathway (KP) in Huntington’s disease (HD) pathogenesis. Quantifying KP metabolites in HD biofluids is desirable, both to study pathobiology, and as a potential source of biomarkers to quantify pathway dysfunction and evaluate the biochemical impa...

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Literature Corpus work
1050deed-0382-5be0-8d6f-68ddfabbf465
DOI
10.1101/2020.08.06.20169524
Open publication

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Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington’s diseaseDOI 10.1101/2020.08.06.20169524
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