Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease.

Journal of neurochemistry - 1 Jul 2021

Rodrigues Filipe B, Byrne Lauren M, Lowe Alexander J, Tortelli Rosanna, Heins Mariette, Flik Gunnar, Johnson Eileanoir B, De Vita Enrico, Scahill Rachael I, Giorgini Flaviano, Wild Edward J

Abstract excerpt

Converging lines of evidence from several models, and post-mortem human brain tissue studies, support the involvement of the kynurenine pathway (KP) in Huntington's disease (HD) pathogenesis. Quantifying KP metabolites in HD biofluids is desirable, both to study pathobiology and as a potential source of biomarkers to quantify pathway dysfunction and evaluate the biochemical impact of therapeutic interventions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

Share to Cohort Studies

Share to Huntington Disease

Share to Kynurenine

Share to Magnetic Resonance Imaging

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 33797782
DOI: 10.1111/jnc.15360
PMCID: PMC8375100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease.PMID 33797782Read ↗

Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington’s diseaseSemantic proximity Read ↗

Cerebrospinal Fluid Biomarkers for Huntington’s DiseaseSemantic proximity Read ↗

Dysregulation of the Kynurenine Pathway in Relapsing Remitting Multiple Sclerosis and Its Correlations With Progressive NeurodegenerationSemantic proximity Read ↗

Age‐ and disease‐specific changes of the kynurenine pathway in Parkinson’s and Alzheimer’s diseaseSemantic proximity Read ↗

Sex differences in peripheral and central dysregulation of the kynurenine pathway in Parkinson’s diseaseSemantic proximity Read ↗

Kynurenine Pathway Metabolites as Biomarkers in Alzheimer’s DiseaseSemantic proximity Read ↗

Redefining Roles: A Paradigm Shift in Tryptophan-Kynurenine Metabolism for Innovative Clinical ApplicationsSemantic proximity Read ↗

Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease.Semantic proximity Read ↗

What, When and How to Measure-Peripheral Biomarkers in Therapy of Huntington's Disease.Semantic proximity Read ↗

The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative diseaseSemantic proximity Read ↗

Brain Versus Blood: A Systematic Review on the Concordance Between Peripheral and Central Kynurenine Pathway Measures in Psychiatric Disorders.Semantic proximity Read ↗

Kynurenine pathway in Parkinson's disease—An updateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.