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Kynurenine Pathway Metabolites as Biomarkers in Alzheimer’s Disease

19 Jan 2022

Abstract excerpt

), and other pathological changes in the brain. The kynurenine pathway (KP) and several of its metabolites, especially quinolinic acid (QA), are considered to be involved in the neuropathogenesis of AD. The important metabolites and key enzymes show significant importance in neuroinflammation and AD. Meanwhile, the discovery of changed levels of KP metabolites in patients with AD suggests that KP metabolites may...

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PMID: 35096208
DOI: 10.1155/2022/9484217

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