Article

Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy

2024-09-07

Abstract excerpt

<h4>ABSTRACT</h4> Gamma delta (γδ) T cells are defined by their unique ability to recognize a limited repertoire of non-peptide, non-MHC-associated antigens on transformed and pathogen-infected cells. In addition to their lack of alloreactivity, γδ T cells exhibit properties distinct from other lymphocyte subsets, prompting significant interest in their development as an off-the-shelf cellular immunotherapeutic....

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Literature Corpus work: 10260313-560a-5407-b3f3-694da7ea70a1
DOI: 10.1101/2024.09.03.611042

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