Article

A Microgel-Based Platform for Tunable Expansion and Function of γδ T-cells

2026-07-24

Abstract excerpt

Current γδ T-cell expansion protocols often sacrifice functionality for yield and largely ignore the context of activation. Here we utilize a tunable alginate microgel system functionalized with anti-CD3 and co-stimulatory antibodies (αCD28 or αCD2) to investigate the impact of biochemical signaling and substrate mechanics on γδ T-cell activation. Microgel-mediated expansion was compared to conventional soluble an...

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Identifiers and source

Literature Corpus work: 66bdaf48-b04d-5d7f-a776-afb3cc537dbb
DOI: 10.64898/2026.07.23.740340

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