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Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling

17 Aug 2021

Abstract excerpt

Organoids culture provides unique opportunities to study human diseases and to complement animal models. Several organs and tissues can be in vitro cultured in 3D structures resembling in vivo tissue organization. Organoids culture contains most of the cell types of the original tissue and are maintained by growth factors mimicking the in vivo state. However, the system is yet not fully understood, and specific...

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PMID: 34404908
DOI: 10.1038/s41598-021-96321-8

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