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Regulation of the TLR4 pathway by the SENP3 gene in a model of hypoxia-induced inflammation

2022-12-12

Abstract excerpt

Microglia are innate immune cells of the central nervous system. After the onset of Ischemic stroke, excessive neuroinflammation would cause further damage to brain tissue, which is characterized by microglial activation and the release of inflammatory cytokines. Earlier studies have shown that SENP3 is raised in the brain tissue of ischemic stroke animals. We further demonstrated that SENP3 induced TLR activation...

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Literature Corpus work
0f5d7d6d-bc26-544d-8460-0a58e64d0ea8
DOI
10.21203/rs.3.rs-2346433/v1
Open publication

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Regulation of the TLR4 pathway by the SENP3 gene in a model of hypoxia-induced inflammationDOI 10.21203/rs.3.rs-2346433/v1
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