Article

MFG-E8 attenuates neuro-inflammation in subarachnoid hemorrhage through driving microglial M2 polarization via modulating Integrin β3/SOCS3/STAT3 signaling pathway

2020-03-20

Abstract excerpt

<title>Abstract</title> <p>Background Increasing evidence suggests microglial polarization plays an important role in the pathological processes of neuro-inflammation following subarachnoid hemorrhage (SAH). Previous studies indicated that milk fat globule-EGF factor-8 (MFG-E8) has the potential in anti-apoptosis and anti-inflammation in cerebral ischemia. However, the effects of MFG-E8 on microglial polarization...

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Literature Corpus work: 47e7642a-fb57-5fd3-bf0a-56c0b680c444
DOI: 10.21203/rs.3.rs-18171/v1

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