Article

Power analysis of transcriptome-wide association study: implications for practical protocol choice

2020-07-20

Abstract excerpt

The transcriptome-wide association study (TWAS) has emerged as one of several promising techniques for integrating multi-scale ‘omics’ data into traditional genome-wide association studies (GWAS). Unlike GWAS, which associates phenotypic variance directly with genetic variants, TWAS uses a reference dataset to train a predictive model for gene expressions, which allows it to associate phenotype with variants throu...

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Literature Corpus work: 0f250a25-d4c6-5203-a9c9-7a2c2181ab52
DOI: 10.1101/2020.07.19.211151

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