Article

A computational approach to estimating nondisjunction frequency in <i>Saccharomyces cerevisiae</i>

2015-08-13

Abstract excerpt

Errors segregating homologous chromosomes during meiosis result in the formation of aneuploid gametes and are the largest contributing factor to birth defects and spontaneous abortions in humans. Saccharomyces cerevisiae has long served as a model organism for studying the gene network supporting normal chromosome segregation. Current methods of measuring homolog nondisjunction frequencies are laborious and invol...

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Literature Corpus work: 0f022c14-3e09-5bb1-86ef-e8a7b20b9bf8
DOI: 10.1101/024570

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