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Article

A unified model of aneuploid karyotype dynamics

2026-02-20

Abstract excerpt

Aneuploidies—whole-chromosome copy number imbalances arising from nondisjunction—underlie numerous congenital and somatic disorders, but unlike many other disease-causing variants, they can readily revert back to euploidy through subsequent errors of the same type. The extent to which this inherent plasticity impacts the stability and persistence of aneuploid karyotypes in populations remains poorly understood, a...

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Literature Corpus work
863aed1d-231d-52e4-8270-8c15c345f21b
DOI
10.64898/2026.02.20.707056
Open publication

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A unified model of aneuploid karyotype dynamicsDOI 10.64898/2026.02.20.707056
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