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Article

RecombineX: A generalized computational framework for automatic high-throughput gamete genotyping and tetrad-based recombination analysis.

PLoS genetics - 1 May 2022

Li Jing, Llorente Bertrand, Liti Gianni, Yue Jia-Xing

Abstract excerpt

Meiotic recombination is an essential biological process that ensures faithful chromosome segregation and promotes parental allele shuffling. Tetrad analysis is a powerful approach to quantify the genetic makeups and recombination landscapes of meiotic products. Here we present RecombineX (https://github.com/yjx1217/RecombineX), a generalized computational framework that automates the full workflow of marker...

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PMID: 35533184
DOI: 10.1371/journal.pgen.1010047
PMCID: PMC9119626

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