Article

GPR143, a novel immunohistochemical marker for renal tumors with <i>FLCN/TSC/MTOR-TFE</i> alterations

2026-04-10

Abstract excerpt

Although several ancillary tests are available in limited laboratories, diagnosis of microphthalmia (MiT)/TFE family translocation renal cell carcinoma (tRCC) could be challenging due to diverse and overlapping tumor morphology and the lack of reliable biomarkers. GPNMB has been recently identified as a diagnostic marker for various renal neoplasms with FLCN/TSC/mTOR-TFE alterations. However, the sensitivity and...

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Literature Corpus work: 0efca73d-5514-5b05-94a3-32d6fadd9cf4
DOI: 10.64898/2026.04.06.26350070

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