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Proteogenomic characterization of MiT family translocation renal cell carcinoma

5 Dec 2022

Abstract excerpt

Microphthalmia transcription factor (MiT) family translocation renal cell carcinoma (tRCC) is a rare type of kidney cancer, which is not well characterized. Here we show the comprehensive proteogenomic analysis of tRCC tumors and normal adjacent tissues to elucidate the molecular landscape of this disease. Our study reveals that defective DNA repair plays an important role in tRCC carcinogenesis and progression....

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PMID: 36470859
DOI: 10.1038/s41467-022-34460-w

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