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Article

Clinical and Molecular Characterization of Microphthalmia-associated Transcription Factor (MITF)-related Renal Cell Carcinoma.

Urology - 1 Mar 2021

Lang Martin, Vocke Cathy D, Ricketts Christopher J, Metwalli Adam R, Ball Mark W, Schmidt Laura S, Linehan William M

Abstract excerpt

OBJECTIVES: To characterize the clinical presentation, genomic alterations, pathologic phenotype and clinical management of microphthalmia-associated transcription factor (MITF) familial renal cell carcinoma (RCC), caused by a member of the TFE3, TFEB, and MITF family of transcription factor genes. METHODS: The clinical presentation, family history, tumor histopathology, and surgical management were evaluated and...

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Identifiers

PMID: 33242557
DOI: 10.1016/j.urology.2020.11.025
PMCID: PMC8728951

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