Article

Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells

2022-01-20

Abstract excerpt

<h4>SUMMARY</h4> Injured neurons in the adult mammalian central nervous system often die and seldom regenerate axons. To uncover transcriptional pathways that could ameliorate these disappointing responses we analyzed three interventions that increase survival and regeneration of mouse retinal ganglion cells (RGCs) following optic nerve crush (ONC) injury, albeit not to a clinically useful extent. We assessed gen...

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Literature Corpus work: 0eed8a6c-a21f-5206-91dc-2bb8700bca71
DOI: 10.1101/2022.01.19.476970

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