Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptome profiling of the rat retina after optic nerve transection

29 Jun 2016

Abstract excerpt

Glaucoma is a group of eye diseases characterized by alterations in the contour of the optic nerve head (ONH), with corresponding visual field defects and progressive loss of retinal ganglion cells (RGCs). This progressive RGC death is considered to originate in axonal injury caused by compression of the axon bundles in the ONH. However, the molecular pathomechanisms of axonal injury-induced RGC death are not yet...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glaucoma and retinal disorders
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27353354
DOI: 10.1038/srep28736

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptome profiling of the rat retina after optic nerve transectionPMID 27353354Read ↗

RNA Sequence Reveals Mouse Retinal Transcriptome Changes Early after Axonal InjurySemantic proximity Read ↗

Commonalities of optic nerve injury and glaucoma-induced neurodegeneration: Insights from transcriptome-wide studiesSemantic proximity Read ↗

Laser capture microdissection-based single-cell RNA sequencing reveals optic nerve crush-related early mRNA alterations in retinal ganglion cellsSemantic proximity Read ↗

Retinal Genomic Fabrics Remodeling after Optic Nerve InjurySemantic proximity Read ↗

Early Gene Expression Changes in the Retinal Ganglion Cell Layer of a Rat Glaucoma ModelSemantic proximity Read ↗

Core Transcription Programs Controlling Injury-Induced Neurodegeneration of Retinal Ganglion CellsSemantic proximity Read ↗

Changes in Gene Expression in Experimental Glaucoma and Optic Nerve Transection: The Equilibrium between Protective and Detrimental MechanismsSemantic proximity Read ↗

Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Experimental Glaucoma and Optic Nerve CrushSemantic proximity Read ↗

Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cellsSemantic proximity Read ↗

Zebrafish optic nerve injury results in systemic retinal ganglion cell dedifferentiationSemantic proximity Read ↗

Experimental Glaucoma and Optic Nerve Transection Induce Simultaneous Upregulation of Proapoptotic and Prosurvival GenesSemantic proximity Read ↗

Global Gene Expression Changes in Rat Retinal Ganglion Cells in Experimental GlaucomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.