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Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses

2020-08-05

Abstract excerpt

Retinal Müller glia (MG) can act as stem-like cells to generate new neurons in both zebrafish and mice. In zebrafish, retinal regeneration is innate and robust, resulting in the replacement of lost neurons and restoration of visual function. In mice, exogenous stimulation of MG is required to reveal a dormant and, to date, limited regenerative capacity. Zebrafish studies have been key in revealing factors that pro...

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Literature Corpus work
e5b079cf-9ec3-5004-8705-1260437e5b33
DOI
10.1101/2020.08.04.236299
Open publication

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Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responsesDOI 10.1101/2020.08.04.236299
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