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Article

Zebrafish optic nerve injury results in systemic retinal ganglion cell dedifferentiation

2025-04-15

Abstract excerpt

Retinal ganglion cells (RGCs) are the sole projection neurons connecting the retina to the brain and therefore play a critical role in vision. Death of RGCs during glaucoma, optic neuropathies and after ocular trauma results in irreversible loss of vision as RGCs do not regenerate in the human eye. Moreover, there are no FDA approved therapies that prevent RGC death and/or promote RGC survival in the diseased or i...

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Literature Corpus work
a5bef9e9-ed57-50e9-818a-897b7b55ecac
DOI
10.1101/2025.04.09.646875
Open publication

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Zebrafish optic nerve injury results in systemic retinal ganglion cell dedifferentiationDOI 10.1101/2025.04.09.646875
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