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Article

Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD.

Molecular metabolism - 1 Aug 2021

Mashek Douglas G

Abstract excerpt

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is defined by the abundance of lipid droplets (LDs) in hepatocytes. While historically considered simply depots for energy storage, LDs are increasingly recognized to impact a wide range of biological processes that influence cellular metabolism, signaling, and function. While progress has been made toward understanding the factors leading to LD accumulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33186758
DOI: 10.1016/j.molmet.2020.101115
PMCID: PMC8324678

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