Article

Hepatic miR-93 promotes the pathogenesis of metabolic dysfunction-associated steatotic liver disease by suppressing SIRT1

2024-10-17

Abstract excerpt

<title>Abstract</title><p>Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a global health challenge with limited therapeutic options, and its molecular mechanisms remain poorly understood. Here, we identify microRNA-93 (miR-93) as a critical regulator of MASLD progression. miR-93 was markedly upregulated in liver tissues from both MASLD patients and diet-induced obese mice. miR-93 knock...

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Literature Corpus work: 5af0f5b2-04b9-540c-96d2-869d315473a8
DOI: 10.21203/rs.3.rs-5202645/v1

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