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Structural Relationship of Flavin Mononucleotide (FMN) and Type I Nitroreductase (NTR) of <em>Trypanosoma cruzi</em> in Resistance Testing with Benznidazole and Nifurtimox

2018-06-01

Abstract excerpt

The Chagas disease (CD) is an endemic infectious disease in a large part of Latin America. This disease is characterized by the fact of being caused by the parasite Trypanosoma cruzi. Some symptoms of this disease are cardiopathies and gastrointestinal problems. Therefore, the commonly used treatment consists of nitro drugs such as benznidazole and nifurtimox, which target the nitroreductase enzyme that docks to t...

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Literature Corpus work
0ece5be9-4ce5-5a8d-91b3-ba33e8599310
DOI
10.20944/preprints201806.0012.v1
Open publication

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Structural Relationship of Flavin Mononucleotide (FMN) and Type I Nitroreductase (NTR) of <em>Trypanosoma cruzi</em> in Resistance Testing with Benznidazole and NifurtimoxDOI 10.20944/preprints201806.0012.v1
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