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Development of new PCR protocols to detect genetic diversity in the metronidazole metabolism genes in susceptible and refractory clinical samples of Giardia duodenalis

2023-12-15

Abstract excerpt

<title>Abstract</title> <p>Purpose Investigating the genetic variation in thioredoxin reductase (TrxR) and nitroreductase (NR) genes in both treatment-resistant and sensitive <italic>Giardia duodenalis</italic> isolates can provide valuable information in identifying potential markers of resistance to metronidazole. The rapid increase in metronidazole treatment failures suggests the presence of genetic resistanc...

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Literature Corpus work
670ff0cc-6a24-59c3-a631-2fba91e0a2c8
DOI
10.21203/rs.3.rs-3702191/v1
Open publication

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Development of new PCR protocols to detect genetic diversity in the metronidazole metabolism genes in susceptible and refractory clinical samples of Giardia duodenalisDOI 10.21203/rs.3.rs-3702191/v1
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