Article

Liver developmental microenvironment promotes iHSC generation from human iPSCs

2025-03-27

Abstract excerpt

<title>Abstract</title> <p>Hepatic stellate cells (HSCs) are liver-specific mesenchymal cells that play a crucial role in liver formation and regeneration, as well as in different pathological diseases. However, the limited source of primary HSCs (pHSCs) and the suboptimal functionality of induced HSCs (iHSCs) by existing methods restrict their application in biomedical modeling. We developed a de novo differenti...

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Literature Corpus work: c4a66975-ed8c-54a6-86cf-f750c1312cc4
DOI: 10.21203/rs.3.rs-6182569/v1

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