Article

ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury

2022-02-24

Abstract excerpt

Unlike many mammalian vital organs, the lung exhibits a robust, multifaceted regenerative response to severe injuries such as influenza infection, which primarily targets epithelial cells in the airways and alveoli. Quiescent lung-resident epithelial progenitors proliferate, migrate, and differentiate following lung injury, participating in two distinct reparative pathways: functionally beneficial regeneration and...

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Identifiers and source

Literature Corpus work: 0ec36af2-b60b-57f3-aece-490a0895528f
DOI: 10.1101/2022.02.23.481695

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