Article

Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice

2022-07-28

Abstract excerpt

Durable reconstitution of the injured distal lung epithelium with pluripotent stem cell (PSC) derivatives, if realized, would represent a promising potential therapy for diseases that result from alveolar damage. Here we differentiate murine PSCs in vitro into self-renewing lung epithelial progenitors able to engraft into the injured distal lung epithelium of immunocompetent, syngeneic mouse recipients. Emulating...

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Literature Corpus work: 4714cb3d-0877-5f6c-98b2-cac60742370d
DOI: 10.1101/2022.07.26.501591

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