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Predicting cognitive ability in ageing cohorts using Type 2 diabetes genetic risk.

Diabetic medicine : a journal of the British Diabetic Association - 1 Jun 2014

Luciano M, Mõttus R, Harris S E, Davies G, Payton A, Ollier W E R, Horan M A, Starr J M, Porteous D J, Pendleton N, Deary I J

Abstract excerpt

AIMS: To investigate whether there is overlap in the genetic determinants of Type 2 diabetes and cognitive ageing by testing whether a genetic risk score for Type 2 diabetes can predict variation in cognitive function in older people without dementia. METHODS: Type 2 diabetes genetic risk scores were estimated using various single nucleotide polymorphism significance inclusion criteria from an initial genome-wide...

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PMID: 24344862
DOI: 10.1111/dme.12389

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