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The SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epithelia

2021-02-04

Abstract excerpt

The novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) caused the devastating ongoing coronavirus disease-2019 (COVID-19) pandemic which poses a great threat to global public health. The spike (S) polypeptide of SARS-CoV-2 consists of the S1 and S2 subunits and is processed by cellular proteases at the S1/S2 boundary. The inclusion of the 4 amino acids (PRRA) at the S1/S2 boundary forms a furin cle...

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Literature Corpus work
0e5489e2-33fc-53b6-a9a6-6c30850a4ba8
DOI
10.1101/2021.02.03.429670
Open publication

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The SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epitheliaDOI 10.1101/2021.02.03.429670
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