Article

Blocking abundant RNA transcripts by high-affinity oligonucleotides during transcriptome library preparation

2022-03-11

Abstract excerpt

<h4>ABSTRACT</h4> RNA sequencing has become the gold standard for transcriptome analysis but has an inherent limitation of challenging quantification of low-abundant transcripts. In contrast to microarray technology, RNA sequencing reads are proportionally divided in function of transcript abundance. Therefore, low-abundant RNAs compete against highly abundant - and sometimes non-informative - RNA species. We dev...

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Literature Corpus work: a08dcfb8-bee3-5f4d-8c8f-2325ae5f4d13
DOI: 10.1101/2022.03.11.483910

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