Article

Structure of <i>Allium</i> lachrymatory factor synthase elucidates catalysis on sulfenic acid substrate

2017-05-30

Abstract excerpt

Natural lachrymatory effects are invoked by small volatile S -oxide compounds. They are produced through alkene sulfenic acids by the action of lachrymatory factor synthase (LFS). Here we present the crystal structures of onion LFS ( Ac LFS) revealed in solute-free and two solute-stabilized forms. Each structure adopts a single seven-stranded helix-grip fold possessing an internal pocket. Mutagenesis analysis lo...

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Literature Corpus work: 0e23b17b-1a1e-575b-936c-c5b59dab49c1
DOI: 10.1101/142687

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