Article
Extensive profiling of the expressions of tRNAs and tRNA-derived fragments (tRFs) reveals the complexities of tRNA and tRF populations in plants.
Science China. Life sciences - 1 Apr 2021
Ma Xuan, Liu Chunyan, Kong Xiaocong, Liu Jing, Zhang Siju, Liang Shanshan, Luan Weijiang, Cao Xiaofeng
Abstract excerpt
Evidence is emerging that tRNA-derived fragments (tRFs) are regulatory molecules. Studies of tRFs in plants have been based on conventional small RNA sequencing, and focused on profiling of tRF-5 and tRF-3 species. A more comprehensive and quantitative analysis of the entire tRF population is highly necessary. Here, we employ tRNA-seq and YAMAT-seq, and develop a bioinformatics tool to comprehensively profile the...
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