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Matching tRNA modifications in humans to their known and predicted enzymes

10 Jan 2019

Abstract excerpt

tRNA are post-transcriptionally modified by chemical modifications that affect all aspects of tRNA biology. An increasing number of mutations underlying human genetic diseases map to genes encoding for tRNA modification enzymes. However, our knowledge on human tRNA-modification genes remains fragmentary and the most comprehensive RNA modification database currently contains information on approximately 20% of...

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PMID: 30698754
DOI: 10.1093/nar/gkz011

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