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tiRNAs & tRFs Biogenesis and Regulation of Diseases: A Review

25 Jan 2019

Abstract excerpt

tiRNAs & tRFs are a class of small molecular noncoding tRNA derived from precise processing of mature or precursor tRNAs. Most tiRNAs & tRFs described originate from nucleus-encoded tRNAs, and only a few tiRNAs and tRFs have been reported. They have been suggested to play important roles in inhibiting protein synthesis, regulating gene expression, priming viral reverse transcriptases, and the modulation of DNA...

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PMID: 30678615
DOI: 10.2174/0929867326666190124123831

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