Article

Lipooligosaccharide, Vag8, and pertussis toxin of <i>Bordetella pertussis</i> cooperatively cause coughing in mice

2020-12-26

Abstract excerpt

<h4>Summary</h4> Whooping cough, a contagious respiratory disease caused by Bordetella pertussis , is characterized by paroxysmal coughing; however, the mechanism has not been studied because of the lack of versatile animal models that reproduce the cough. Here, we present a mouse model that reproduces coughing after intranasal inoculation with the bacteria or its components and demonstrate that lipooligosacchar...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0e0c1c5d-3bef-538f-8c07-7ee9a63d93d8
DOI: 10.1101/2020.12.25.424096

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lipooligosaccharide, Vag8, and pertussis toxin of <i>Bordetella pertussis</i> cooperatively cause coughing in miceDOI 10.1101/2020.12.25.424096Read

Contribution of pertussis toxin to the pathogenesis of pertussis disease: Graphical Abstract Figure.Semantic proximity Read

Bps polysaccharide of <i>Bordetella pertussis</i> resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts <i>Escherichia coli</i> into a respiratory pathogenSemantic proximity Read

The History of Pertussis ToxinSemantic proximity Read

Localization of regions of a <i>Bordetella pertussis</i> autotransporter, Vag8, interacting with C1 inhibitorSemantic proximity Read

A dual role for PGLYRP1 in host defense and immune regulation during <i>B. pertussis</i> infectionSemantic proximity Read

<i>Mycobacterium tuberculosis</i> sulfolipid-1 (Sl-1) increases the excitability of mouse and human TRPV1-positive sensory neurons in a YM254890-reversible fashionSemantic proximity Read

<i>Bordetella</i> Spp. Utilize T3SS To Promote Secretion of IL1RA Leading to Long-Term Persistent InfectionsSemantic proximity Read

Fatal Pertussis in the Neonatal Mouse Model Is Associated with Pertussis Toxin-Mediated Pathology beyond the AirwaysSemantic proximity Read

Inflammasome Activation by Adenylate Cyclase Toxin Directs Th17 Responses and Protection against <i>Bordetella pertussis</i>Semantic proximity Read

Pertussis: a matter of immune modulationSemantic proximity Read

Pertussis Toxin and Adenylate Cyclase Toxin: Key Virulence Factors of <i>Bordetella Pertussis</i> and Cell Biology ToolsSemantic proximity Read

Investigating the role of TRPA1 and TRPV1 ion channels in the cough reflexSemantic proximity Read